19 November 2015
miReven scientists have been awarded a $530,000 NHMRC Development Grant to advance miR-7 as a novel cancer therapeutic. Chief Investigators on the project Prof. Peter Leedman and Dr Christopher Wraight will apply the funding to the devel ... READ MORE
24 July 2014
MiReven scientists have published a review on Micro RNA-7 in the June 2014 edition of The International Journal of Biochemistry & Cell Biology. The article, entitled "microRNA-7: A tumor suppressor miRNA with therapeutic potential", ... READ MORE
30 April 2014
Perth, Western Australia (30 April, 2014) MiReven Pty Ltd (mireven.com.au), an Australian microRNA company commercialising discoveries from the Harry Perkins Institute of Medical Research on the anti-cancer potential of miR-7, announces t ... READ MORE
14 November 2013
Perth, Western Australia, November 13, 2013 – MiReven, an Australian microRNA company commercialising discoveries from the Western Australian Institute for Medical Research (WAIMR) on the anti-cancer potential of miR-7, has won the 2 ... READ MORE
12 September 2013
MiReven is pleased to announce that the company has been selected as a finalist in the 2013 Western Australia Innovator of the Year Awards. ... READ MORE
12 February 2013
Publication in Biochemical and Biophysical Research Communications shows miRNA-7-5p inhibits melanoma cell migration and invasion MiReven launches its new website at www.mireven.com.au Perth, Western Australia, February 12, 2013 – ... READ MORE
25 October 2012
MiReven, an Australian microRNA company commercialising discoveries from the Western Australian Institute for Medical Research (WAIMR) on the anti-cancer potential of miR-7, today announced the publication in the journal PLOS One of a study ... READ MORE
27 August 2012
MiReven, an Australian microRNA company commercialising discoveries from the Western Australian Institute for Medical Research (WAIMR) on the anti-cancer potential of miR-7, today announced that it had received a further AU$500K investment ... READ MORE
Silence Therapeutics signs collaboration with MiReven Pty Ltd to evaluate delivery of novel microRNA-based therapeutics
22 August 2012
London, UK, August 22, 2012 – Silence Therapeutics plc (AIM: SLN) (“Silence”), a leading RNA interference (RNAi) therapeutics company, announces that it has signed an agreement with MiReven Pty Ltd (“MiReven”), to assess the deliv ... READ MORE
Giles KM, Brown RA, Ganda C, Podgorny MJ, Candy PA, Wintle LC, Richardson KL, Kalinowski FC, Stuart LM, Epis MR, Haass NK, Herlyn M, Leedman PJ.
microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB.
Oncotarget. 2016 May 17.
Horsham JL, Ganda C, Kalinowski FC, Brown RA, Epis MR, Leedman PJ (2015)
microRNA-7: a miRNA with expanding roles in development and disease.
Int J Biochem Cell Biol. 2015 Nov 4. pii: S1357-2725(15)30056-X. doi: 10.1016/j.biocel.2015.11.001. [Epub ahead of print] Review.
Horsham JL, Kalinowski FC, Epis MR, Ganda C, Brown RA, Leedman PJ (2015)
Clinical Potential of microRNA-7 in Cancer.
J Clin Med. 2015 Aug 25;4(9):1668-87. doi: 10.3390/jcm4091668. Review.
Kalinowski FC, Brown RA, Ganda C, Giles KM, Epis MR, Horsham J, Leedman PJ (2014)
microRNA-7: A tumor suppressor miRNA with therapeutic potential.
Int J Biochem Cell Biol. 2014 Jun 5. pii: S1357-2725(14)00198-8.
doi: 10.1016/j.biocel.2014.05.040. [Epub ahead of print]
Giles KM, Brown R, Epis MR, Kalinowski FC, Leedman PJ (2012)
miRNA-7-5p inhibits melanoma cell migration and invasion.
Biochem. Biophys. Res. Commun. Dec 1. pii: S0006-291X(12)02261-9.
doi: 10.1016/j.bbrc.2012.11.086. [Epub ahead of print]
Kalinowski FC, Giles KM, Candy PA, Ali A, Ganda C, Epis MR, Webster RJ, Leedman PJ. (2012)
Regulation of Epidermal Growth Factor Receptor Signaling and Erlotinib Sensitivity in Head and Neck Cancer Cells by miR-7.
PLoS ONE 7(10): e47067.
Giles KM, Barker A, Zhang PM, Epis MR, Leedman PJ (2011)
MicroRNA regulation of growth factor receptor signaling in human cancer cells.
Methods Mol. Biol. 676:147-63.
doi: 10.1007/978-1-60761-863-8_11. PubMed PMID: 20931396.
Barker A, Giles KM, Epis MR, Zhang PM, Kalinowski F, Leedman PJ (2010)
Regulation of ErbB receptor signalling in cancer cells by microRNA.
Curr. Opin. Pharmacol. 10(6):655-61.
Epub 2010 Sep 21. Review. PubMed PMID: 20864407.
Webster RJ, Giles KM, Price KJ, Zhang PM, Mattick JS, Leedman PJ (2009)
Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7.
J. Biol. Chem. 284(9):5731-41.
Epub 2008 Dec 10. PubMed PMID: 19073608.